SCIENTIFIC PROGRAM

13th National Haemostasis Update (NHU 2024)
September 6, 2024 (Friday)
(The timings mentioned are as per the Indian Standard Time - IST)
07:30 - 08:50 Registration
Hall A 
08:50 - 09:00 Welcome Note
Time (IST) Topic Speaker/Chair
09:00 - 09:40 Plenary 1
09:00 - 09:30 Redefining Goals of Haemophilia Therapy in the Era of Non-Factor Replacement TBD
09:30 - 09:40 Discussion
Hall A  Hall B 
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
09:45 - 11:00 (20 mins talk & 5 mins discussion each) Scientific Session 1A Theme: Von Willebrand Disease Scientific Session 1B Theme: MSK
09:45 - 10:10 Challenges in von Willebrand Disease Diagnosis in Low- and Middle-Income Countries: The Way Forward. Shrimathi Shetty, ICMR- National Institute of Immunohematology, Mumbai.
10:10 - 10:35 Shifting Paradigms: Genomic Diagnosis as an Effective Substitute For Functional Testing in Von Willebrand Disease for Low Middle Income Countries Michelle Lavin, National Coagulation Centre, St. James's Hospital, Dublin.
10:35 - 11:00 Improving von Willebrand Disease Outcomes in Low- and Middle-Income Countries Jameela Sathar, Hospital Ampang, Ampang.
11:00 - 11:30 Tea Break with Poster Viewing Tea Break with Poster Viewing
11:35 - 12:35 Symposium I Symposium II
12:35 - 13:30 Lunch Lunch
13:35 - 14:30 Scientific Session 2A Theme: Bridging Trends in Haemophilia Scientific Session 2B (Nursing)
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
13:35 - 14:00 (20 mins talk & 5 mins discussion) Emerging Trends in The Management Acquired Haemophilia A Nguyen Thi Mai, National Institute of Hematology and Blood Transfusion, Hanoi
14:00 - 14:30 Panel Discussion - Newly Diagnosed Haemophilia: Insights from Different Countries Moderator: Rattapan Lamool, Pramongkut Hospital, Bangkok. Panelists: Sein Win, Yangon General Hospital, Yangon. Thamudika Vithanage, National Hospital of Sri Lanka, Colombo and Referral Centre, Dhaka. Bishesh Sharma Poudyal, Civil Service Hospital, Kathmandu.
Hall A 
14:35 - 15:15 Plenary 2
15:05 - 15:15 Discussion
Hall A  Hall B 
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
15:20 - 16:20 Sponsored Symposium III Sponsored Symposium IV
16:20 - 16:50 Tea Break with Poster Viewing Tea Break with Poster Viewing
Hall A  Hall B 
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
16:55 - 18:10 (20 mins talk & 5 mins discussion each) Scientific Session 3A Theme: Difficult Bleeds in Haemophilia Care: Challenges and Solutions Scientific Session 3B Theme: Advances in Diagnosing Bleeding Disorders
16:55 - 17:20 Recurrent Pseudotumours in Haemophilia: Evidence Based management The Institutional Approach for Diagnosis and Management of Children with Bleeding of Unknown Cause Nongnuch Sirachainan, Ramathibodi Hospital, Bangkok.
17:20 - 17:45 Optimal Treatment Strategies in Prevention of Intracranial Bleeding in Haemophilia Patients Haemostasis Lab in the Era of NFCs. "Bert Verbruggen, Radboud University Nijmegen Medical Centre, The Netherlands.
17:45 - 18:10 Managing Major Bleeds in Inhibitor-Positive Haemophilia: Challenges and Innovations Darintr Sosothikul, Chulalongkorn University, Bangkok. How to Make Diagnosis of Bleeding Disorders Accessible and Cost Effective?
13:00 Onwards Dinner with Invited Guests
4th Annual Scientific Meeting (AHAD-AP 2024)
HALL A
Time(ICT) Topic Speaker/Chair
09:00 - 09:40 Plenary 3
09:00 - 09:30 Capitalizing on Registries: Advancing Haemophilia Care Through Research Marijke Van Den Berg,
University Medical Center, Utrecht.
09:30 - 09:40 Discussion
HALL A HALL B
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
09:45 - 11:00
(20 mins talk & 5 mins discussion each)		 Scientific Session 4A Theme: NFC and Gene Therapy - Future of Clotting Factor Concentrates Scientific Session 4B Theme: Nursing
09:45 - 10:10 Gene Therapy for Haemophilia: An Update from the Asia Pacific Perspective
10:10 - 10:35 The Future of Haemophilia Treatment: Positioning of EHLs & CFCs Pratima Choudhry,
University College London, London.
10:35 - 11:00
(7 mins talk & 3 mins rebuttal each, 5 mins combined discussion ) 		Debate: Navigating Haemophilia A with Inhibitors Moderator:
TBD
NFC The Way Forward:
Tadashi Matsushita
Nagoya University, Nagoya.
ITI The Way Forward:
TBD
11:00 - 11:30 Tea Break with Poster Viewing Tea Break with Poster Viewing
Hall A Hall B
11:35 - 12:35 Sponsored Symposium V Sponsored Symposium VI
12:35 - 13:30 Lunch Lunch
Hall A Hall B
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
13:35 - 14:35 Oral Scientific Abstracts: Physicians and Lab Oral Scientific Abstracts: Nursing and MSK
14:40 - 15:20 Plenary 4
14:40 - 15:10 Adapting Care for Women and Girls with Haemophilia; A Lifecycle Approach
15:10 - 15:20 Discussion
15:25 - 16:25 Sponsored Symposium VII Sponsored Symposium VIII
16:25 - 16:55 Tea Break with Poster Viewing Tea Break with Poster Viewing
17:00 - 17:50
(20 mins talk & 5 mins discussion each) 		Scientific Session 5A
Theme: Insights From Bleeding Disorder Registries in the Asia Pacific Region and Annual Global Survey		 Scientific Session 5B
Theme: Diverse Challenges in Bleeding Disorders: In the Old and The Young
17:00 - 17:25 Australia: A Model for National Bleeding Disorders Registries Cardiovascular Problems and Comorbidities in Aging Patients with Haemophilia (PwH)
17:25 - 17:50 Prophylactic Trends in Haemophilia: A Macroeconomic Analysis Using Annual Global Survey Data M Joseph John,
Christian Medical College Ludhiana, Ludhiana.		 Management of Fetus and Newborn with Haemophilia
4th Annual Scientific Meeting (AHAD-AP 2024)
HALL A
Time (IST) Topic Speaker/Chair
09:00 - 10:30 Scientific Session 6
Theme: Specific Challenges in Inhibitor Positive PwH
09:00 - 09:25 Predicting Inhibitor Development in Haemophilia
09:25 - 09:50 Management of Haemophilia B with Inhibitors
09:50 - 10:35 Panel Discussion:
How I Manage Surgeries in PwH with Inhibitors		 Moderator:
TBD
Panelists:
Aby Abraham,
Christian Medical College Vellore, Vellore.
Heng Joo Ng,
Singapore General Hospital, Singapore.
Seungmin Hahn,
Yonsei University College of Medicine, Seoul.
Azusa Nagao,
Ogikubo Hospital, Tokyo.
10:35 - 11:05 Tea Break
11:10 - 12:40 Scientific Session 7
Theme: Hot Topics
12:40 - 12:50 Closing Session
13:00 Onwards Lunch and Departure
Time(ICT) HALL A
08:20-08:30 Welcome note: AHAD-AP ASM 2023
Alok Srivastava, Christian Medical College Vellore, Vellore.
Darintr Sosothikul, Chulalongkorn University, Bangkok.
Co-Presidents AHAD-AP ASM 2023
08:30-09:10 Plenary 1
Chair: Alok Srivastava, Christian Medical College Vellore, Vellore.
08:30-09:00 Extended half-life CFCs and theirimpact on haemophilia care
Speaker: Flora Peyvandi, University of Milan, Milan.
09:00-09:10 Discussion
Hall A Hall B
09:15-10:45 Scientific Session 1a
Theme: Prophylaxis – CFC
Chair: Joyce Lam Ching Mei, KK Women's and Children's Hospital, Singapore.		 Scientific Session 1b
Theme: Lab diagnosis
Chair: Tien Sim Leng, Singapore General Hospital, Singapore. Wong Wan Hui,Singapore General Hospital, Singapore.
09:15-09:45 Initiating prophylaxis in young children – when and how ?
Speaker: Seungmin Hahn, Yonsei University College of Medicine, Seoul.		 Challenges with the Laboratory Diagnosis of Bleeding Disorders
Speaker: Tien Sim Leng, Singapore General Hospital, Singapore
09:45-10:15 Clinical Outcomes of Prophylaxis with Low-Dose Pharmacokinetic-Guided Extended Half Life Factor VIII Concentrates
Speaker: Darintr Sosothikul, Chulalongkorn University, Bangkok.		 Recovery assays and limitations – SHL / EHL
Speaker: Yingyong Chinthamitr, Siriraj hospital, Bangkok.
10:15-10:45 Optimizing Prophylaxis in Resource-Challenged Settings
Speaker:NguyenThi Mai, National Institute of Hematology and Blood Transfusion, Hanoi.		 Lab monitoring for surgery withnon-CFC products
Speaker: Nitty Mathews, Christian Medical College Vellore, Vellore.
10:45-11:15 Tea Break
11:15-12:30 Scientific Session 2a
Theme: Inhibitors in Haemophilia
Chair: Runhui Wu, Children’s Hospital, Capital Medical University, Beijing.		 Scientific Session 2b
Theme: Using registries to improve haemophilia care
Chair: Shashikant Apte, Sahyadri Specialty Hospital, Pune.
11:15-11:40 Prevalence of inhibitors – How toenhance surveillance?
Speaker: Ng HengJoo, Singapore General Hospital, Singapore.		 National registries
Speakers: Japan: Takeshi Matsumoto, Mie University Hospital, Mie Prefecture.
Thailand: Ampaiwan Chuansumrit, Ramathibodi Hospital, Bangkok.
11:40-12:05 Immune Tolerance Therapy for Inhibitors – An Asian Perspective
Speaker: Li Zekun, Children's Hospital, Capital Medical University Beijing.		 Nation Registries
Speakers: South Korea- Jung Woo Han, Yonsie University Health System, Seoul.
Australia- HuyenTran, The Alfred hospital & Monash Medical Centre, Melbourne.
12:05-12:30 Prevention of Bleeds in Persons with Haemophilia with Inhibitors
Speaker:Renchi Yang, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin.		 APBDR
Speaker: Azusa Nagao, Ogikubo Hospital, Tokyo.
12:30-13:00 Lunch
13:00-14:00 Sponsored Symposium I- Sanofi Sponsored Symposium II- Roche
Hall A
14:00-14:40 Plenary 2
Chair: Darintr Sosothikul, Chulalongkorn University, Bangkok.
14:00-14:30 Addressing the diagnostic gap in haemophilia and other inherited bleeding disorders - what are the possibilities?
Speaker: Keith Gomez, Royal Free Hospital, London.
14:30-14:40 Discussion
Hall A Hall B
14:45-16:15 Scientific Session 3a – Women with Bleeding Disorders
Chair: Chean Sophal, National Pediatric Hospital, Phnom Penh.		 Scientific Session 3b – Nursing
Chair: Lim Chiew Ying, KK Women’s and Children’s Hospital, Singapore.
14:45-15:15 Womenwith Bleeding Disorders – Diagnostic Issues
Speaker:Tan Chuen Wen, Singapore General Hospital, Singapore.		 Nursing principles of care- bleeding disorders
Speaker: Jamie Chase, John Hunter Childrens Hospital, New South Wales.
15:15-15:45 Management of Menorrhagia in Women with Bleeding Disorders
Speaker: Bundarika Suwanawiboon, Siriraj Hospital, Bangkok.		 Panel Discussion- Role of Haemophilia Nurse in HTCs across Asia Pacific.
Moderator: Abraham Sunder Singh, Christian Medical College, Vellore.
Panelists:
1.Yeam Shin Yen, Singapore General Hospital, Singapore.
2.Pakawan Wongweerawattanakoon, Ramathibodi Hospital, Bangkok.
3.Devika Danekhu, Civil Service Hospital, Kathmandu.
15:45-16:15 Management of Pregnancies and Surgeries in Women with Bleeding Disorders
Speaker: Briony Cutts, Royal Women's hospital Melbourne.		 Training and preparation of a familyfor self-infusion at home.
Speaker: Wu Siting, BeijingChildren's Hospital, Beijing.
16:30-17:00 Moderated poster session with tea
Moderators: Tien SimLeng, Singapore General Hospital, Singapore Rungrote Natesirinilkul, Chiang Mai University, Chiang Mai.
Hall A Hall B
17:00-18:15 Scientific Session 4a – Surgery in haemophilia
Chair: Hideyuki Takedani, National Hospital Organization Tsuruga Medical Center, Fukui.		 Scientific Session 4b – MSK Outcome assessment including PROs
Chair: Judy AnnDavid, Christian Medical College, Vellore.
17:00-17:25 Management of Dental Procedures in Patients with Haemophilia
Speaker: Thanaporn Thongjood, Ramathibodi Hospital, Bangkok.		 MSK Outcomes assessment- Overview
Speaker: Tachit Jiravichitchai, Ramathibodi Hospital, Bangkok.
17:25-17:50 Perioperative haemostasis managementin haemophilia
Speaker: Jae Joon Han, Kyung Hee University, Seoul.		 MSK outcome assessment– what is practical.
Speakers:
a) Taiwan: Yeu-Chin Chen, Tri-Service General Hospital, Taipei.
b) Indonesia: Rizky Kusumawardhani, Dr. Cipto Mangunkusumo Hospital, Jakarta.
5 mins Q&A
c) India: Naveen Cherian Thomas, Christian Medical College, Vellore.
d) Malaysia: Haishini Mageswaran, Hospital Ampang, Ampang.
5 mins Q&A
17:50-18:15 Joint replacement surgery inhaemophilia – What considerations?
Speaker: Shashikant Apte, Sahyadri Specialty Hospital, Pune.
18:15-19:15 Sponsored symposium III with high tea - Takeda Sponsored symposium IV with high tea - Chugai
19:30 Dinner with Invited guests
Time(ICT) HALL A
08:30-09:10 Plenary 3
Chair: Pantep Angchaisuksiri, Ramathibodi Hospital, Bangkok.
08:30-09:00 Non-CFC products for haemophilia –how will they change the management paradigm?
Speaker: Johnny Mahlangu, University of the Witwatersrand, Johannesburg.
09:00-09:10 Discussion
Hall A Hall B
09:15-10:45 Scientific Session 5a – Use of Non-CFC haemostasis products
Chair: Ampaiwan Chuansumrit, Ramathibodi Hospital, Bangkok.		 Scientific Session 5b – Comprehensive Management
Chair: Alison Street, Monash University, Melbourne.
09:15-09:45 Emicizumab – Real world data -Standard & Alternative doses
Speaker: Keiji Nogami, Nara Medical University, Nara.		 Role of WFH in the comprehensive management of haemophilia in the Asia Pacific.
Speakers: Toong Youtananukorn, World Federation of Hemophilia, Montreal.
Hazri Aris, World Federation of Hemophilia, KualaLumpur.
09:45-10:15 The ‘Universal’ haemostasis productsfor haemophilia A/B with and without inhibitors – What can be their impact?
Speaker: Alok Srivastava, Christian Medical College Vellore, Vellore.		 Ultrasoundin clinical decision making - Perspectives & Application
Speaker:Madhavi Kandagaddala, Christian Medical College Vellore, Vellore.
10:15-10:45 Management of Breakthrough Bleeds and Surgery in the Era of Non-CFC Products.
Speaker: Jiaan-Der Wang, Taichung Veterans General Hospital, Taichung.		 Patient Empowerment – Are we doing enough ?
Speaker: Ekawat Suwantaroj, Bangkok.
10:45-11:15 Tea Break
Hall A Hall B
11:15-12:25 Scientific Session 6a – Scientific Abstracts- Physicians and Lab
Moderators: M Joseph John, Christian Medical College, Ludhiana.
Patcharee Kamwilaisak, Khon Kaen University, Khon Kaen.		 Scientific Session 6b – Scientific Abstracts- Nursing and MSK
Moderators: Judy AnnDavid, Christian Medical College, Vellore
Anjalin D’Souza, Manipal Academy of Higher Education, Manipal
11:15-11:20 Introduction Introduction
11:20-11:30 Role of Low Dose prophylaxis of Anti Hemophilic Factor in Haemophilia.
Presenter: Sudipta Nandi, Maulana Azad Medical College, New Delhi.		 Effectiveness of Myofascial therapy (MFT) and Conventional physiotherapy (CPT) with intermittent prophylaxis on Joint Health in Haemophilic Arthropathy- A Proof of Concept Randomized Control Trial.
Presenter: Diksha Sarwan, Christian Medical College and Hospital, Ludhiana.
11:30-11:40 Successful removal of high titer inhibitor in a patient with severe haemophilia A by low dose rituximab combined with low dose FVIII immune tolerance therapy.
Presenter: Li Zhou, The Second Affiliated Hospital of Anhui Medical University, Anhui.		 Estimated cost per bleed saved: On-Demand (OD) versus Low-dose Prophylaxis (LDP) for Indonesian children with Severe Haemophilia A (SHA).
Presenter: Christina Hill-Zabala, Grifols Asia Pacific, Singapore.
11:40-11:50 Barriers to cascade screening and prenatal testing in families with inherited bleeding disorders.
Presenter: Archit Sunil Pandharipande, Post Graduate Institute of Child Health, Noida.		 Out-of-pocket expenditure incurred during treatment of Haemophilia at a government facility in North India.
Presenter: Manju Singh, Post Graduate Institute of Child Health, Noida.
11:50-12:00 Managing surgical procedures in children with inherited bleeding disorders; a single center experience.
Presenter: Eby P Baby, Post Graduate Institute of Child Health, Noida.		 Burden of Care and Quality of Life Among Caregivers of Filipino Children with Haemophilia Before and During the COVID-19 Pandemic: A Cross-Sectional Study.
Presenter: Noah Sacluti, University of Santo Tomas Hospital, Manila.
12:00-12:10 Management of severe haemophilia with inhibitors to factor VIII with recurrent retroperitoneal bleed.
Presenter: Vijayshree Muthukumar, Apollo Hospital, Chennai.		 Rehabilitation for the improvement of functional status in hemophiliacs.
Presenter: Sudipta Nandi, Maulana Azad Medical College, New Delhi.
12:10-12:20 Validation test for Haemophilia self-screening tool In South Kalimantan, Indonesia.
Presenter: Wulandewi Marhaeni, Universitas Lambung Mangkurat, South Kaimantan.		 Sufferings beyond the Physical impact of Haemophilia- A mixed method study on personal, social, economic domains and its association with quality of life in patients with haemophilia (PWH) and their caregivers (WE CARE)
Presenter: Shivani Bhanwra, Christian Medical College and Hospital, Ludhiana.
12:20-12:25 Conclusion Conclusion
12:30-13:00 Lunch
13:00-14:00 Sponsored Symposium V - Novo Nordisk
Hall A
14:00-14:40 Plenary 4
Chair: Ponlapat Rojnuckarin, Chulalongkorn University, Bangkok
14:00-14:30 Radiological assessment of joint –what is possible and what is useful ?
Speaker: Andrea S Doria, The Hospital for Sick Children, Toronto.
14:30-14:40 Discussion
Hall A
14:45-15:45 Scientific Session 7 – Country/Region Presentations
Chair: Theera Ruchutrakool, Siriraj Hospital, Bangkok.
Haemophilia Care
Cambodia: Chean Sophal, National Pediatric Hospital, Phnom Penh.
China: Guoqing Liu, Beijing Children's Hospital, Beijing.
Sri Lanka: Visaka Ratnamalala, National Hospital of Sri Lanka, Colombo.
Bangladesh: Akhil Ranjon Biswas, Dhaka Medical College, Dhaka.
Philippines: Flerida Hernandez, University of Santo Tomas, Manila.
Myanmar: Aye Aye Khaing, Yangon Children Hospital, Yangon.
15:45-16:15 Education and Training - Role of AHAD-AP
Speaker: Alison Street, Monash University, Melbourne.
16:15-17:00 Scientific Session 8 – Hot Topics (Industry presentations)
Chair: Nongnuch Sirachainan, Ramathibodi Hospital, Bangkok.
16:15-16:30 Concizumab prophylaxis in patients with haemophilia A or B without inhibitors: Efficacy and safety results from the primary analysis of the phase 3 explorer8 study.
Speaker: Myriam Dardikh, Novo Nordisk, Dubai.
16:30-16:45 A Phase 3 study (ATLAS-PPX) to evaluate efficacy and safety of fitusiran, an siRNA therapeutic, in people with hemophilia A or B who have switched from prior factor or bypassing agent prophylaxis.
Speaker: Alok Srivastava, Christian Medical College Vellore, Vellore.
16:45-17:00 Phase 3 prospective, randomized, controlled, open-label, multicenter, crossover study of recombinant ADAMTS13 in patients with congenital thrombotic thrombocytopenic purpura.
Speaker: Laura Ochoa, Takeda, Singapore.
17:15-17:30 Closing session
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SCIENTIFIC PROGRAM

13th National Haemostasis Update (NHU 2024)
September 6, 2024 (Friday)
(The timings mentioned are as per the Indian Standard Time - IST)
07:30 - 08:50 Registration
Hall A 
08:50 - 09:00 Welcome Note
Time (IST) Topic Speaker/Chair
09:00 - 09:40 Plenary 1
09:00 - 09:30 Redefining Goals of Haemophilia Therapy in the Era of Non-Factor Replacement TBD
09:30 - 09:40 Discussion
Hall A  Hall B 
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
09:45 - 11:00 (20 mins talk & 5 mins discussion each) Scientific Session 1A Theme: Von Willebrand Disease Scientific Session 1B Theme: MSK
09:45 - 10:10 Challenges in von Willebrand Disease Diagnosis in Low- and Middle-Income Countries: The Way Forward. Shrimathi Shetty, ICMR- National Institute of Immunohematology, Mumbai.
10:10 - 10:35 Shifting Paradigms: Genomic Diagnosis as an Effective Substitute For Functional Testing in Von Willebrand Disease for Low Middle Income Countries Michelle Lavin, National Coagulation Centre, St. James's Hospital, Dublin.
10:35 - 11:00 Improving von Willebrand Disease Outcomes in Low- and Middle-Income Countries Jameela Sathar, Hospital Ampang, Ampang.
11:00 - 11:30 Tea Break with Poster Viewing Tea Break with Poster Viewing
11:35 - 12:35 Symposium I Symposium II
12:35 - 13:30 Lunch Lunch
13:35 - 14:30 Scientific Session 2A Theme: Bridging Trends in Haemophilia Scientific Session 2B (Nursing)
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
13:35 - 14:00 (20 mins talk & 5 mins discussion) Emerging Trends in The Management Acquired Haemophilia A Nguyen Thi Mai, National Institute of Hematology and Blood Transfusion, Hanoi
14:00 - 14:30 Panel Discussion - Newly Diagnosed Haemophilia: Insights from Different Countries Moderator: Rattapan Lamool, Pramongkut Hospital, Bangkok. Panelists: Sein Win, Yangon General Hospital, Yangon. Thamudika Vithanage, National Hospital of Sri Lanka, Colombo and Referral Centre, Dhaka. Bishesh Sharma Poudyal, Civil Service Hospital, Kathmandu.
Hall A 
14:35 - 15:15 Plenary 2
15:05 - 15:15 Discussion
Hall A  Hall B 
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
15:20 - 16:20 Sponsored Symposium III Sponsored Symposium IV
16:20 - 16:50 Tea Break with Poster Viewing Tea Break with Poster Viewing
Hall A  Hall B 
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
16:55 - 18:10 (20 mins talk & 5 mins discussion each) Scientific Session 3A Theme: Difficult Bleeds in Haemophilia Care: Challenges and Solutions Scientific Session 3B Theme: Advances in Diagnosing Bleeding Disorders
16:55 - 17:20 Recurrent Pseudotumours in Haemophilia: Evidence Based management The Institutional Approach for Diagnosis and Management of Children with Bleeding of Unknown Cause Nongnuch Sirachainan, Ramathibodi Hospital, Bangkok.
17:20 - 17:45 Optimal Treatment Strategies in Prevention of Intracranial Bleeding in Haemophilia Patients Haemostasis Lab in the Era of NFCs. "Bert Verbruggen, Radboud University Nijmegen Medical Centre, The Netherlands.
17:45 - 18:10 Managing Major Bleeds in Inhibitor-Positive Haemophilia: Challenges and Innovations Darintr Sosothikul, Chulalongkorn University, Bangkok. How to Make Diagnosis of Bleeding Disorders Accessible and Cost Effective?
13:00 Onwards Dinner with Invited Guests
4th Annual Scientific Meeting (AHAD-AP 2024)
HALL A
Time(ICT) Topic Speaker/Chair
09:00 - 09:40 Plenary 3
09:00 - 09:30 Capitalizing on Registries: Advancing Haemophilia Care Through Research Marijke Van Den Berg,
University Medical Center, Utrecht.
09:30 - 09:40 Discussion
HALL A HALL B
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
09:45 - 11:00
(20 mins talk & 5 mins discussion each)		 Scientific Session 4A Theme: NFC and Gene Therapy - Future of Clotting Factor Concentrates Scientific Session 4B Theme: Nursing
09:45 - 10:10 Gene Therapy for Haemophilia: An Update from the Asia Pacific Perspective
10:10 - 10:35 The Future of Haemophilia Treatment: Positioning of EHLs & CFCs Pratima Choudhry,
University College London, London.
10:35 - 11:00
(7 mins talk & 3 mins rebuttal each, 5 mins combined discussion ) 		Debate: Navigating Haemophilia A with Inhibitors Moderator:
TBD
NFC The Way Forward:
Tadashi Matsushita
Nagoya University, Nagoya.
ITI The Way Forward:
TBD
11:00 - 11:30 Tea Break with Poster Viewing Tea Break with Poster Viewing
Hall A Hall B
11:35 - 12:35 Sponsored Symposium V Sponsored Symposium VI
12:35 - 13:30 Lunch Lunch
Hall A Hall B
Time (IST) Topic Speaker/Chair Topic Speaker/Chair
13:35 - 14:35 Oral Scientific Abstracts: Physicians and Lab Oral Scientific Abstracts: Nursing and MSK
14:40 - 15:20 Plenary 4
14:40 - 15:10 Adapting Care for Women and Girls with Haemophilia; A Lifecycle Approach
15:10 - 15:20 Discussion
15:25 - 16:25 Sponsored Symposium VII Sponsored Symposium VIII
16:25 - 16:55 Tea Break with Poster Viewing Tea Break with Poster Viewing
17:00 - 17:50
(20 mins talk & 5 mins discussion each) 		Scientific Session 5A
Theme: Insights From Bleeding Disorder Registries in the Asia Pacific Region and Annual Global Survey		 Scientific Session 5B
Theme: Diverse Challenges in Bleeding Disorders: In the Old and The Young
17:00 - 17:25 Australia: A Model for National Bleeding Disorders Registries Cardiovascular Problems and Comorbidities in Aging Patients with Haemophilia (PwH)
17:25 - 17:50 Prophylactic Trends in Haemophilia: A Macroeconomic Analysis Using Annual Global Survey Data M Joseph John,
Christian Medical College Ludhiana, Ludhiana.		 Management of Fetus and Newborn with Haemophilia
4th Annual Scientific Meeting (AHAD-AP 2024)
HALL A
Time (IST) Topic Speaker/Chair
09:00 - 10:30 Scientific Session 6
Theme: Specific Challenges in Inhibitor Positive PwH
09:00 - 09:25 Predicting Inhibitor Development in Haemophilia
09:25 - 09:50 Management of Haemophilia B with Inhibitors
09:50 - 10:35 Panel Discussion:
How I Manage Surgeries in PwH with Inhibitors		 Moderator:
TBD
Panelists:
Aby Abraham,
Christian Medical College Vellore, Vellore.
Heng Joo Ng,
Singapore General Hospital, Singapore.
Seungmin Hahn,
Yonsei University College of Medicine, Seoul.
Azusa Nagao,
Ogikubo Hospital, Tokyo.
10:35 - 11:05 Tea Break
11:10 - 12:40 Scientific Session 7
Theme: Hot Topics
12:40 - 12:50 Closing Session
13:00 Onwards Lunch and Departure
Time(ICT) HALL A
08:20-08:30 Welcome note: AHAD-AP ASM 2023
Alok Srivastava, Christian Medical College Vellore, Vellore.
Darintr Sosothikul, Chulalongkorn University, Bangkok.
Co-Presidents AHAD-AP ASM 2023
08:30-09:10 Plenary 1
Chair: Alok Srivastava, Christian Medical College Vellore, Vellore.
08:30-09:00 Extended half-life CFCs and theirimpact on haemophilia care
Speaker: Flora Peyvandi, University of Milan, Milan.
09:00-09:10 Discussion
Hall A Hall B
09:15-10:45 Scientific Session 1a
Theme: Prophylaxis – CFC
Chair: Joyce Lam Ching Mei, KK Women's and Children's Hospital, Singapore.		 Scientific Session 1b
Theme: Lab diagnosis
Chair: Tien Sim Leng, Singapore General Hospital, Singapore. Wong Wan Hui,Singapore General Hospital, Singapore.
09:15-09:45 Initiating prophylaxis in young children – when and how ?
Speaker: Seungmin Hahn, Yonsei University College of Medicine, Seoul.		 Challenges with the Laboratory Diagnosis of Bleeding Disorders
Speaker: Tien Sim Leng, Singapore General Hospital, Singapore
09:45-10:15 Clinical Outcomes of Prophylaxis with Low-Dose Pharmacokinetic-Guided Extended Half Life Factor VIII Concentrates
Speaker: Darintr Sosothikul, Chulalongkorn University, Bangkok.		 Recovery assays and limitations – SHL / EHL
Speaker: Yingyong Chinthamitr, Siriraj hospital, Bangkok.
10:15-10:45 Optimizing Prophylaxis in Resource-Challenged Settings
Speaker:NguyenThi Mai, National Institute of Hematology and Blood Transfusion, Hanoi.		 Lab monitoring for surgery withnon-CFC products
Speaker: Nitty Mathews, Christian Medical College Vellore, Vellore.
10:45-11:15 Tea Break
11:15-12:30 Scientific Session 2a
Theme: Inhibitors in Haemophilia
Chair: Runhui Wu, Children’s Hospital, Capital Medical University, Beijing.		 Scientific Session 2b
Theme: Using registries to improve haemophilia care
Chair: Shashikant Apte, Sahyadri Specialty Hospital, Pune.
11:15-11:40 Prevalence of inhibitors – How toenhance surveillance?
Speaker: Ng HengJoo, Singapore General Hospital, Singapore.		 National registries
Speakers: Japan: Takeshi Matsumoto, Mie University Hospital, Mie Prefecture.
Thailand: Ampaiwan Chuansumrit, Ramathibodi Hospital, Bangkok.
11:40-12:05 Immune Tolerance Therapy for Inhibitors – An Asian Perspective
Speaker: Li Zekun, Children's Hospital, Capital Medical University Beijing.		 Nation Registries
Speakers: South Korea- Jung Woo Han, Yonsie University Health System, Seoul.
Australia- HuyenTran, The Alfred hospital & Monash Medical Centre, Melbourne.
12:05-12:30 Prevention of Bleeds in Persons with Haemophilia with Inhibitors
Speaker:Renchi Yang, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin.		 APBDR
Speaker: Azusa Nagao, Ogikubo Hospital, Tokyo.
12:30-13:00 Lunch
13:00-14:00 Sponsored Symposium I- Sanofi Sponsored Symposium II- Roche
Hall A
14:00-14:40 Plenary 2
Chair: Darintr Sosothikul, Chulalongkorn University, Bangkok.
14:00-14:30 Addressing the diagnostic gap in haemophilia and other inherited bleeding disorders - what are the possibilities?
Speaker: Keith Gomez, Royal Free Hospital, London.
14:30-14:40 Discussion
Hall A Hall B
14:45-16:15 Scientific Session 3a – Women with Bleeding Disorders
Chair: Chean Sophal, National Pediatric Hospital, Phnom Penh.		 Scientific Session 3b – Nursing
Chair: Lim Chiew Ying, KK Women’s and Children’s Hospital, Singapore.
14:45-15:15 Womenwith Bleeding Disorders – Diagnostic Issues
Speaker:Tan Chuen Wen, Singapore General Hospital, Singapore.		 Nursing principles of care- bleeding disorders
Speaker: Jamie Chase, John Hunter Childrens Hospital, New South Wales.
15:15-15:45 Management of Menorrhagia in Women with Bleeding Disorders
Speaker: Bundarika Suwanawiboon, Siriraj Hospital, Bangkok.		 Panel Discussion- Role of Haemophilia Nurse in HTCs across Asia Pacific.
Moderator: Abraham Sunder Singh, Christian Medical College, Vellore.
Panelists:
1.Yeam Shin Yen, Singapore General Hospital, Singapore.
2.Pakawan Wongweerawattanakoon, Ramathibodi Hospital, Bangkok.
3.Devika Danekhu, Civil Service Hospital, Kathmandu.
15:45-16:15 Management of Pregnancies and Surgeries in Women with Bleeding Disorders
Speaker: Briony Cutts, Royal Women's hospital Melbourne.		 Training and preparation of a familyfor self-infusion at home.
Speaker: Wu Siting, BeijingChildren's Hospital, Beijing.
16:30-17:00 Moderated poster session with tea
Moderators: Tien SimLeng, Singapore General Hospital, Singapore Rungrote Natesirinilkul, Chiang Mai University, Chiang Mai.
Hall A Hall B
17:00-18:15 Scientific Session 4a – Surgery in haemophilia
Chair: Hideyuki Takedani, National Hospital Organization Tsuruga Medical Center, Fukui.		 Scientific Session 4b – MSK Outcome assessment including PROs
Chair: Judy AnnDavid, Christian Medical College, Vellore.
17:00-17:25 Management of Dental Procedures in Patients with Haemophilia
Speaker: Thanaporn Thongjood, Ramathibodi Hospital, Bangkok.		 MSK Outcomes assessment- Overview
Speaker: Tachit Jiravichitchai, Ramathibodi Hospital, Bangkok.
17:25-17:50 Perioperative haemostasis managementin haemophilia
Speaker: Jae Joon Han, Kyung Hee University, Seoul.		 MSK outcome assessment– what is practical.
Speakers:
a) Taiwan: Yeu-Chin Chen, Tri-Service General Hospital, Taipei.
b) Indonesia: Rizky Kusumawardhani, Dr. Cipto Mangunkusumo Hospital, Jakarta.
5 mins Q&A
c) India: Naveen Cherian Thomas, Christian Medical College, Vellore.
d) Malaysia: Haishini Mageswaran, Hospital Ampang, Ampang.
5 mins Q&A
17:50-18:15 Joint replacement surgery inhaemophilia – What considerations?
Speaker: Shashikant Apte, Sahyadri Specialty Hospital, Pune.
18:15-19:15 Sponsored symposium III with high tea - Takeda Sponsored symposium IV with high tea - Chugai
19:30 Dinner with Invited guests
Time(ICT) HALL A
08:30-09:10 Plenary 3
Chair: Pantep Angchaisuksiri, Ramathibodi Hospital, Bangkok.
08:30-09:00 Non-CFC products for haemophilia –how will they change the management paradigm?
Speaker: Johnny Mahlangu, University of the Witwatersrand, Johannesburg.
09:00-09:10 Discussion
Hall A Hall B
09:15-10:45 Scientific Session 5a – Use of Non-CFC haemostasis products
Chair: Ampaiwan Chuansumrit, Ramathibodi Hospital, Bangkok.		 Scientific Session 5b – Comprehensive Management
Chair: Alison Street, Monash University, Melbourne.
09:15-09:45 Emicizumab – Real world data -Standard & Alternative doses
Speaker: Keiji Nogami, Nara Medical University, Nara.		 Role of WFH in the comprehensive management of haemophilia in the Asia Pacific.
Speakers: Toong Youtananukorn, World Federation of Hemophilia, Montreal.
Hazri Aris, World Federation of Hemophilia, KualaLumpur.
09:45-10:15 The ‘Universal’ haemostasis productsfor haemophilia A/B with and without inhibitors – What can be their impact?
Speaker: Alok Srivastava, Christian Medical College Vellore, Vellore.		 Ultrasoundin clinical decision making - Perspectives & Application
Speaker:Madhavi Kandagaddala, Christian Medical College Vellore, Vellore.
10:15-10:45 Management of Breakthrough Bleeds and Surgery in the Era of Non-CFC Products.
Speaker: Jiaan-Der Wang, Taichung Veterans General Hospital, Taichung.		 Patient Empowerment – Are we doing enough ?
Speaker: Ekawat Suwantaroj, Bangkok.
10:45-11:15 Tea Break
Hall A Hall B
11:15-12:25 Scientific Session 6a – Scientific Abstracts- Physicians and Lab
Moderators: M Joseph John, Christian Medical College, Ludhiana.
Patcharee Kamwilaisak, Khon Kaen University, Khon Kaen.		 Scientific Session 6b – Scientific Abstracts- Nursing and MSK
Moderators: Judy AnnDavid, Christian Medical College, Vellore
Anjalin D’Souza, Manipal Academy of Higher Education, Manipal
11:15-11:20 Introduction Introduction
11:20-11:30 Role of Low Dose prophylaxis of Anti Hemophilic Factor in Haemophilia.
Presenter: Sudipta Nandi, Maulana Azad Medical College, New Delhi.		 Effectiveness of Myofascial therapy (MFT) and Conventional physiotherapy (CPT) with intermittent prophylaxis on Joint Health in Haemophilic Arthropathy- A Proof of Concept Randomized Control Trial.
Presenter: Diksha Sarwan, Christian Medical College and Hospital, Ludhiana.
11:30-11:40 Successful removal of high titer inhibitor in a patient with severe haemophilia A by low dose rituximab combined with low dose FVIII immune tolerance therapy.
Presenter: Li Zhou, The Second Affiliated Hospital of Anhui Medical University, Anhui.		 Estimated cost per bleed saved: On-Demand (OD) versus Low-dose Prophylaxis (LDP) for Indonesian children with Severe Haemophilia A (SHA).
Presenter: Christina Hill-Zabala, Grifols Asia Pacific, Singapore.
11:40-11:50 Barriers to cascade screening and prenatal testing in families with inherited bleeding disorders.
Presenter: Archit Sunil Pandharipande, Post Graduate Institute of Child Health, Noida.		 Out-of-pocket expenditure incurred during treatment of Haemophilia at a government facility in North India.
Presenter: Manju Singh, Post Graduate Institute of Child Health, Noida.
11:50-12:00 Managing surgical procedures in children with inherited bleeding disorders; a single center experience.
Presenter: Eby P Baby, Post Graduate Institute of Child Health, Noida.		 Burden of Care and Quality of Life Among Caregivers of Filipino Children with Haemophilia Before and During the COVID-19 Pandemic: A Cross-Sectional Study.
Presenter: Noah Sacluti, University of Santo Tomas Hospital, Manila.
12:00-12:10 Management of severe haemophilia with inhibitors to factor VIII with recurrent retroperitoneal bleed.
Presenter: Vijayshree Muthukumar, Apollo Hospital, Chennai.		 Rehabilitation for the improvement of functional status in hemophiliacs.
Presenter: Sudipta Nandi, Maulana Azad Medical College, New Delhi.
12:10-12:20 Validation test for Haemophilia self-screening tool In South Kalimantan, Indonesia.
Presenter: Wulandewi Marhaeni, Universitas Lambung Mangkurat, South Kaimantan.		 Sufferings beyond the Physical impact of Haemophilia- A mixed method study on personal, social, economic domains and its association with quality of life in patients with haemophilia (PWH) and their caregivers (WE CARE)
Presenter: Shivani Bhanwra, Christian Medical College and Hospital, Ludhiana.
12:20-12:25 Conclusion Conclusion
12:30-13:00 Lunch
13:00-14:00 Sponsored Symposium V - Novo Nordisk
Hall A
14:00-14:40 Plenary 4
Chair: Ponlapat Rojnuckarin, Chulalongkorn University, Bangkok
14:00-14:30 Radiological assessment of joint –what is possible and what is useful ?
Speaker: Andrea S Doria, The Hospital for Sick Children, Toronto.
14:30-14:40 Discussion
Hall A
14:45-15:45 Scientific Session 7 – Country/Region Presentations
Chair: Theera Ruchutrakool, Siriraj Hospital, Bangkok.
Haemophilia Care
Cambodia: Chean Sophal, National Pediatric Hospital, Phnom Penh.
China: Guoqing Liu, Beijing Children's Hospital, Beijing.
Sri Lanka: Visaka Ratnamalala, National Hospital of Sri Lanka, Colombo.
Bangladesh: Akhil Ranjon Biswas, Dhaka Medical College, Dhaka.
Philippines: Flerida Hernandez, University of Santo Tomas, Manila.
Myanmar: Aye Aye Khaing, Yangon Children Hospital, Yangon.
15:45-16:15 Education and Training - Role of AHAD-AP
Speaker: Alison Street, Monash University, Melbourne.
16:15-17:00 Scientific Session 8 – Hot Topics (Industry presentations)
Chair: Nongnuch Sirachainan, Ramathibodi Hospital, Bangkok.
16:15-16:30 Concizumab prophylaxis in patients with haemophilia A or B without inhibitors: Efficacy and safety results from the primary analysis of the phase 3 explorer8 study.
Speaker: Myriam Dardikh, Novo Nordisk, Dubai.
16:30-16:45 A Phase 3 study (ATLAS-PPX) to evaluate efficacy and safety of fitusiran, an siRNA therapeutic, in people with hemophilia A or B who have switched from prior factor or bypassing agent prophylaxis.
Speaker: Alok Srivastava, Christian Medical College Vellore, Vellore.
16:45-17:00 Phase 3 prospective, randomized, controlled, open-label, multicenter, crossover study of recombinant ADAMTS13 in patients with congenital thrombotic thrombocytopenic purpura.
Speaker: Laura Ochoa, Takeda, Singapore.
17:15-17:30 Closing session
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